Systematic review and meta-analysis of Internet interventions for smoking cessation among adults

Systematic review and meta-analysis of Internet interventions for smoking cessation among adults

Graham AL, Carpenter KM, Cha S, Cole S, Jacobs MA, Raskob M, Cole-Lewis H. Systematic review and meta-analysis of Internet interventions for smoking cessation among adults. Substance Abuse and Rehabilitation. In press.

This systematic review sought to evaluate the effectiveness of Internet interventions in promoting smoking cessation among adult tobacco users, particularly in reference to other forms of intervention recommended in cessation treatment guidelines. This review examined randomized trials published from 1990 through April 2015 and used a mixed automated and manual search strategy. Combinations of “Internet,” “web-based,” and “smoking cessation intervention” and related keywords were used to ensure broad coverage of published studies.

Forty randomized trials involving 98,530 participants were included. Most trials had low risk of bias in most domains. Pooled results of largely static Internet interventions compared to print materials were not significant; comparisons of interactive Internet interventions compared to print materials were significant. No significant effects were observed in pooled studies of Internet interventions compared to face-to-face counseling or telephone counseling. The majority of trials compared different types of Internet interventions; clinical and statistical heterogeneity was high. Studies among young adults showed the most robust effects; 2/3 of the remaining comparisons yielded non-significant effects in favor of the experimental condition. Results of this review suggest that Internet interventions have an important role to play in the arsenal of tobacco dependence treatments.